Name | Trimebutine Maleate Salt |
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Synonyms |
UNII:2A051GM4YM
3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester,Trimebutine maleate salt (4a,5a,17b)-4,5-Epoxy-3,17-dihydroxyandrost-2-ene-2-carbonitrile 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate Polybutin 2a-Cyano-4a,5a-epoxyandrostan-17b-ol-3-one 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate (2Z)-2-butenedioate (1:1) Desopan Trilostane Modrenal EINECS 251-845-9 (1-Ethyl-1-phenyl-2-(3,4,5-trimethoxybenzoyloxy)ethyl)dimethylammonium hydrogen maleate Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester, (2Z)-2-butenedioate (1:1) 3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate TM 906 {Maleate} Benzoic acid, 3,4,5-trimethoxy-, β-(dimethylamino)-β-ethylphenethyl ester, maleate (1:1) MFCD00133874 Trimebutine Maleate MODRASTANE Debridat 2-(Dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate (2Z)-but-2-enedioate (1:1) Trimebutine Maleate Salt (4α,5α,17β)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4α,5α,17β)- 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester Modrefen 3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester maleate salt Vetoryl 4α,5-Epoxy-3,17β-dihydroxy-5α-androst-2-ene-2-carbonitrile Recutin Modulon Trimebutine (maleate) |
Description | Trimebutine maleate is a drug with antimuscarinic and weak mu opioid agonist effects.Target: Opioid ReceptorTrimebutine is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain [1]. The major product from drug metabolism of trimebutine in human beings is nor-trimebutine, which comes from removal of one of the methyl groups attached to nitrogen. Trimebutine exerts its effects in part due to causing a premature activation of phase III of the migrating motor complex in the digestive tract [2, 3]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 497.8±45.0 °C at 760 mmHg |
Melting Point | 122-124ºC |
Molecular Formula | C26H33NO9 |
Molecular Weight | 503.54 |
Flash Point | 254.8±28.7 °C |
PSA | 131.83000 |
LogP | 3.61 |
Vapour Pressure | 0.0±2.9 mmHg at 25°C |
Index of Refraction | 1.610 |
Storage condition | 2-8°C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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Hazard Codes | C |
Risk Phrases | R34 |
Safety Phrases | 26-27-36/37/39-45 |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | DI0360000 |
HS Code | 2922199090 |
HS Code | 2922199090 |
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Summary | 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |