Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Bexarotene
Price:
Purity: 98.0%
Stocking Period: Inquiry
Contact: Tom

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Bexarotene
Price: ￥298.0/10mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Bexarotene
Price: $250.0/100mg $300.0/250mg $1000.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Bexarotene 153559-49-0
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

153559-49-0

153559-49-0 structure

153559-49-0 structure

Name: Bexarotene
Chemical Name: bexarotene
CAS Number: 153559-49-0
Molecular Formula: C₂₄H₂₈O₂
Molecular Weight: 348.478
Catalog: Biochemical Inhibitor Metabolism Retinoid Receptor Inhibitor
Create Date: 2018-02-14 08:00:00
Modify Date: 2024-01-02 18:21:18
Bexarotene is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.

Name	bexarotene
Synonyms	Targretin Bexarotene 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid LG 69 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthalenyl)vinyl]benzoic acid Lg 1069 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid Targretyn Bexaroten Targret Benzoic acid, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]- 4-[1-(3,5,5,8,8-Pentamethyl-2-5,8-dihydronaphthyl)vinyl]benzoic acid 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid LGD1069

Description	Bexarotene is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR Research Areas >> Cancer
References	[1]. Vakeva L, Ranki A, Hahtola S.Ten-year experience of bexarotene therapy for cutaneous T-cell lymphoma in Finland.Acta Derm Venereol. 2012 May;92(3):258-63. doi: 10.2340/00015555-1359. [2]. Zhang X, Schlaak M, Fabri M, Mauch C, Kurschat P.Successful Treatment of a Panniculitis-Like Primary Cutaneous T-Cell Lymphoma of the α/β Type with Bexarotene.Case Rep Dermatol. 2012 Jan;4(1):56-60. [3]. Orendas P, Kubatka P, Kajo K, Stollarova N, Kassayova M, Bojkova B, Pec M, Nosal V, Kiskova T, Zihlavnikova K, Karsnakova R.Melatonin enhanced bexarotene efficacy in experimental mammary carcinogenesis.Neoplasma. 2012;59(4):469-74. [4]. Cras A, Politis B, Balitrand N, Darsin-Bettinger D, Boelle PY, Cassinat B, Toubert ME, Chomienne C.Bexarotene via CBP/p300 induces suppression of NF-κB-dependent cell growth and invasion in thyroid cancer.Clin Cancer Res. 2012 Jan 15;18(2):442-53. [5]. Gui Y, et al. Bexarotent attenuated CCI-induced spinal neuroinflammation and neuropathic pain by targeting MKP-1. J Pain. 2019 Jan 17. pii: S1526-5900(18)30607-2.

Density	1.0±0.1 g/cm3
Boiling Point	489.7±44.0 °C at 760 mmHg
Melting Point	230-231ºC
Molecular Formula	C₂₄H₂₈O₂
Molecular Weight	348.478
Flash Point	229.5±23.1 °C
Exact Mass	348.208923
PSA	37.30000
LogP	8.55
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.556

Hazard Codes	Xn
RIDADR	NONH for all modes of transport

Precursor 10
153559-48-9 6683-48-3 153559-45-6 110-03-2
1346970-00-0 6223-78-5 119999-22-3 29020-85-7
108-88-3 167958-79-4
DownStream 0