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62758-13-8

62758-13-8 structure
62758-13-8 structure
  • Name: Resazurin sodium salt
  • Chemical Name: Resazurin sodium salt
  • CAS Number: 62758-13-8
  • Molecular Formula: C12H6NNaO4
  • Molecular Weight: 251.170
  • Catalog: Biochemical Biochemical reagent Biological dye
  • Create Date: 2018-02-08 08:00:00
  • Modify Date: 2024-01-02 17:28:30
  • Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.
Name Resazurin sodium salt
Synonyms 3H-Phenoxazin-3-one, 7-hydroxy-, 10-oxide, sodium salt (1:1)
7-hydroxy-10-oxy-phenoxazin-3-one,sodium-compound
ResazurinGr
EINECS 263-718-5
7-sodiooxy-3H-phenoxazin-3-one 10-oxide
DIAZORESORCINOL
RESAZURIN SODIUM
7-hydroxy-3H-phenoxazin-3-one 10-oxide sodium salt
Sodium 3-oxo-3H-phenoxazin-7-olate 10-oxide
Resazurine
RESAZOIN
REZAZURIN
RESAZURIN NA-SALT
SODIUM RESAZURIN
REISHIMUSHROOM.P.E
7-Hydroxy-10-oxy-phenoxazin-3-on,Natrium-Verbindung
MFCD00005036
Description Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin.
Related Catalog
In Vitro Resazurin sodium salt is commonly used to measure bacterial and eukaryotic cell viability through its reduction to the fluorescent product resorufin. No viable bacteria are detected 24 h post-inoculation following inclusion of Resazurin sodium salt in TSBc cultures of F. tularensis LVS at the concentration of 44 μM. Lowering the Resazurin sodium salt concentration to as little as 4.4 μM still results in a 10-fold reduction in viable F. tularensis LVS compare to growth medium alone. Both Resazurin sodium salt treatments result in a significant decrease in viable F. tularensis LVS bacteria over 22 h. Treatment with Resazurin sodium salt significantly reduces the number of viable F. tularensis LVS bacteria in HEK293 cells 22 h post-infection[1].
Cell Assay F. tularensis is cultured in TSBc supplemented with 44 μM Resazurin sodium salt at 37°C with shaking for 24 h. At select time points, a Spectronic 200 Spectrophotometer is used to measure the absorbance at 600 nm and 570 nm to detect the presence of Resazurin sodium salt and resorufin, respectively. The ratio of these two optical densities is used to evaluate reduction of Resazurin sodium salt to resorufin over time[1].
References

[1]. Schmitt DM, et al. The use of resazurin as a novel antimicrobial agent against Francisella tularensis. Front Cell Infect Microbiol. 2013 Dec 6;3:93.

Boiling Point 477.2ºC at 760 mmHg
Melting Point >200ºC
Molecular Formula C12H6NNaO4
Molecular Weight 251.170
Flash Point 242.4ºC
Exact Mass 251.019455
PSA 78.73000
LogP 2.47010
Storage condition Store at RT.
Stability Stable. Incompatible with strong oxidizing agents.
Water Solubility soluble
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S26-S36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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title: CAS No. 62758-13-8 | Chemsrc address: https://www.chemsrc.com/en/baike/895899.html

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