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Product Name: T-2 TETRAOL
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34114-99-3

34114-99-3 structure

34114-99-3 structure

Name: T-2 Tetraol
Chemical Name: t-2 tetraol
CAS Number: 34114-99-3
Molecular Formula: C₁₅H₂₂O₆
Molecular Weight: 298.332
Catalog: analytical chemistry Standard Food and cosmetics standards
Create Date: 2018-12-08 12:02:55
Modify Date: 2024-01-01 18:09:57
T-2 Tetraol is a metabolite of T-2 toxin, and also a trichothecene mycotoxin, with less toxicity and is unable to induce apoptosis[1][2].

Name	t-2 tetraol
Synonyms	T-4 toxin (3β,4α,8α,12ξ)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, (2α,3α,4β,6β,8β,11β,12ξ)- t-2toxintetraol t-2tetraol

Description	T-2 Tetraol is a metabolite of T-2 toxin, and also a trichothecene mycotoxin, with less toxicity and is unable to induce apoptosis[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Engler KH, et al. A colorimetric technique for detecting trichothecenes and assessing relative potencies. Appl Environ Microbiol. 1999 May;65(5):1854-7. [2]. Islam Z, et al. Structure-function relationship of T-2 toxin and its metabolites in inducing thymic apoptosis in vivo in mice. Biosci Biotechnol Biochem. 1998 Aug;62(8):1492-7.

Density	1.5±0.1 g/cm3
Boiling Point	515.2±50.0 °C at 760 mmHg
Melting Point	125°C- 135 °C
Molecular Formula	C₁₅H₂₂O₆
Molecular Weight	298.332
Flash Point	265.4±30.1 °C
Exact Mass	298.141632
PSA	102.68000
LogP	-0.77
Vapour Pressure	0.0±3.0 mmHg at 25°C
Index of Refraction	1.644
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YC9980000

CHEMICAL NAME :: Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-

CAS REGISTRY NUMBER :: 34114-99-3

LAST UPDATED :: 198910

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C14-H22-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36900 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1300 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 184 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Behavioral - ataxia

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 26,923,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15700 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOXIA6 Toxicon. (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW, UK) V.1- 1962- Volume(issue)/page/year: 24,985,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 34 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: VHTODE Veterinary and Human Toxicology. (American College of Veterinary and Comparative Toxicology, Publication Office, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Volume(issue)/page/year: 25,335,1983

Symbol	GHS02, GHS07
Signal Word	Danger
Hazard Statements	H225-H302 + H312 + H332-H319
Precautionary Statements	P210-P280-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T+: Very toxic;
Risk Phrases	26/27/28-36/37/38
Safety Phrases	22-36/37/39-45
RIDADR	UN2811 6.1/PG 1
RTECS	YC9980000

20181-53-7 structure

20181-53-7

~%

34114-99-3 structure

34114-99-3

Literature: Okazaki; Yoshizawa; Kimura Bioscience, biotechnology, and biochemistry, 1992 , vol. 56, # 3 p. 523 - 524

Precursor 1
20181-53-7
DownStream 1
65180-29-2