Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ACTH(18-39)(HUMAN)
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Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

Nanjing Peptide Biotech Ltd
China
Product Name: Adrenocorticotropic Hormone
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

53917-42-3

53917-42-3 structure

53917-42-3 structure

Name: ACTH (18-39) (human)
Chemical Name: Adrenocorticotropic Hormone
CAS Number: 53917-42-3
Molecular Formula: C₁₁₂H₁₆₅N₂₇O₃₆
Molecular Weight: 2465.67000
Catalog: Peptides
Create Date: 2019-02-16 20:43:20
Modify Date: 2024-01-01 23:43:41
Adrenocorticotropic Hormone (ACTH) (18-39), human is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary.

Name	Adrenocorticotropic Hormone
Synonyms	CLIP ProteoMass™ ACTH Fragment 18-39 MALDI-MS Adrenocorticotropic hormone fragment 18-39 ARG-PRO-VAL-LYS-VAL-TYR-PRO-ASN-GLY-ALA-GLU-ASP-GLU-SER-ALA-GLU-ALA-PHE-PRO-LEU-GLU-PHE: RPVKVYPNGAEDESAEAFPLEF ACTH (18-39) (HUMAN) Adrenocorticotropic Hormone (ACTH) (18-39), human

Description	Adrenocorticotropic Hormone (ACTH) (18-39), human is a corticotropinlike intermediate lobe peptide, which is is produced in the melanotrophs of the intermediate lobe of the pituitary.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease Peptides
In Vitro	The ACTH family of polypeptides consists of ACTH(1-39) (adrenocorticotropin), ACTH (1-13)amide (α-melanotropin;α-MSH); and ACTH (18-39) (corticotropinlike intermediate lobe peptide, CLIP). These polypeptides are derived from a common precursor, proopiomelanocortin. In corticotropic cells of the pars distalis, proopiomelanocortin (POMC) undergoes a series of proteolytic cleavage reactions to yield ACTH (1-39) as a major end product. However, in the melanotropic cells of the pars intermedia, an additional set of proteolytic reactions results in the conversion of ACTH (1-39) to ACTH (1-13) amide and ACTH (18-39). In several species of vertebrates, ACTH (1-13) amide undergoes end product modification to yield mono- and diacetylated forms ofα-MSH as major end products in the pars intermedia[1].
References	[1]. Dores RM, et al. Analysis of ACTH-related and CLIP-related peptides partially purified from the pituitary of the Australian lungfish, Neoceratodus forsteri. Gen Comp Endocrinol. 1990 Jul;79(1):64-73.

Density	1.49g/cm3
Molecular Formula	C₁₁₂H₁₆₅N₂₇O₃₆
Molecular Weight	2465.67000
Exact Mass	2464.19000
PSA	1006.02000
LogP	1.91620
Index of Refraction	1.665
Storage condition	-20℃

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport