17157-12-9

17157-12-9 structure

Name: (2H7)Isoquinoline
Chemical Name: isoquinoline-d7
CAS Number: 17157-12-9
Molecular Formula: C₉D₇N
Molecular Weight: 136.202
Catalog: Research Areas Cancer
Create Date: 2018-03-31 08:00:00
Modify Date: 2024-01-11 22:36:26
Isoquinoline-d7 is the deuterium labeled Isoquinoline[1]. Isoquinoline is an analog of?pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities[2].

Name	isoquinoline-d7
Synonyms	Heptadecylammonium-chlorid D7-isoquinoline heptadecan-1-amine hydrochloride Heptadeuterio-isochinolin Tetra-n-heptadecylammonium Isochinolin-d7 heptadecylamine,hydrochloride (H)Isoquinoline Isoquinoline-d Heptadecylamin,Hydrochlorid

Description	Isoquinoline-d7 is the deuterium labeled Isoquinoline[1]. Isoquinoline is an analog of?pyridine. Isoquinoline structural-based alkaloids, such as tropoloisoquinoline, phthalideisoquinoline, and naphthylisoquinoline has anti-cancer activities[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Zhi-Xing Qing, et al. Anticancer and Reversing Multidrug Resistance Activities of Natural Isoquinoline Alkaloids and Their Structure-activity Relationship. Curr Med Chem

119-65-3

~88%

17157-12-9

Literature: Yamamoto, Mitsuru; Oshima, Koichiro; Matsubara, Seijiro Heterocycles, 2006 , vol. 67, # 1 p. 353 - 359

Precursor 1
119-65-3
DownStream 0