1351692-92-6

1351692-92-6 structure
1351692-92-6 structure
  • Name: Febuxostat acyl glucuronide
  • Chemical Name: (2S,3S,4S,5R,6S)-6-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
  • CAS Number: 1351692-92-6
  • Molecular Formula: C22H24N2O9S
  • Molecular Weight: 492.50
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Xanthine Oxidase
  • Create Date: 2017-09-01 13:40:41
  • Modify Date: 2024-08-16 12:36:59
  • Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].

Name (2S,3S,4S,5R,6S)-6-[2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-1,3-thiazole-5-carbonyl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
Synonyms Febuxostat Acyl-|A-D-glucuronide
2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylate |A-D-Glucopyranuronic Acid
2-(3-Cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylate |A-D-Glucopyranuronic Acid
Description Febuxostat acyl glucuronide (Febuxostat acyl-β-D-glucuronide) is a metabolite of Febuxostat (HY-14268). Febuxostat is a potent, selective and non-purine xanthine oxidase (XO) inhibitor[1].
Related Catalog
References

[1]. Bishoy Kamel, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.  

[2]. Kamel B, et al. Clinical Pharmacokinetics and Pharmacodynamics of Febuxostat. Clin Pharmacokinet. 2017 May;56(5):459-475.  

Molecular Formula C22H24N2O9S
Molecular Weight 492.50
Exact Mass 492.12000
PSA 207.67000
LogP 1.07398