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478963-79-0

478963-79-0 structure
478963-79-0 structure
  • Name: Calcium-Sensing Receptor Antagonists I
  • Chemical Name: 1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
  • CAS Number: 478963-79-0
  • Molecular Formula: C23H24N2O2
  • Molecular Weight: 360.44900
  • Catalog: Signaling Pathways GPCR/G Protein CaSR
  • Create Date: 2018-12-03 09:36:33
  • Modify Date: 2024-01-02 16:14:58
  • Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. IC50 value:Target: CaSRCalcium-Sensing Receptor Antagonists I is useful for osteoporosis and other bone conditions

Name 1-propan-2-yl-4-(4-propan-2-ylphenyl)-6-prop-2-ynoxyquinazolin-2-one
Synonyms CS-0307
1-(1-METHYLETHYL)-4-[4-(1-METHYLETHYL)PHENYL]-6-(2-PROPYN-1-YLOXY)-2(1H)-QUINAZOLINONE
Calcium-Sensing Receptor Antagonists I
Description Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. IC50 value:Target: CaSRCalcium-Sensing Receptor Antagonists I is useful for osteoporosis and other bone conditions
Related Catalog
References

[1]. Widler, Leo et al. 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists.Journal of Medicinal Chemistry(2010),53(5), 2250-2263.

Density 1.085g/cm3
Boiling Point 510.1ºC at 760 mmHg
Molecular Formula C23H24N2O2
Molecular Weight 360.44900
Flash Point 262.299ºC
Exact Mass 360.18400
PSA 44.12000
LogP 4.77980
Index of Refraction 1.572
Storage condition 2-8℃