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99353-00-1

99353-00-1 structure
99353-00-1 structure
  • Name: Methyl rosmarinate
  • Chemical Name: Methyl rosmarinate
  • CAS Number: 99353-00-1
  • Molecular Formula: C19H18O8
  • Molecular Weight: 374.341
  • Catalog: Natural product Lignans
  • Create Date: 2018-02-04 08:00:00
  • Modify Date: 2024-01-08 18:40:08
  • Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase[1].

Name Methyl rosmarinate
Synonyms (2R)-3-(3,4-dihydroxyphenyl)-1-methoxy-1-oxopropan-2-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
(2R)-3-(3,4-Dihydroxyphenyl)-1-methoxy-1-oxo-2-propanyl (2E)-3-(3,4-dihydroxyphenyl)acrylate
Benzenepropanoic acid, α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-, methyl ester, (αR)-
Description Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28 mM for mushroom tyrosinase, and also inhibits a-glucosidase[1].
Related Catalog
Target

IC50: 0.28 mM (mushroom tyrosinase), a -glucosidase[1]

References

[1]. Lin L, et al. Comparative evaluation of rosmarinic acid, methyl rosmarinate and pedalitin isolated from Rabdosia serra (MAXIM.) HARA as inhibitors of tyrosinase and α-glucosidase. Food Chem. 2011 Dec 1;129(3):884-9.

Density 1.5±0.1 g/cm3
Boiling Point 655.4±55.0 °C at 760 mmHg
Molecular Formula C19H18O8
Molecular Weight 374.341
Flash Point 236.5±25.0 °C
Exact Mass 374.100159
PSA 133.52000
LogP 2.12
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.668
Hazard Codes Xi
Precursor  0

DownStream  1