14365-63-0

14365-63-0 structure
14365-63-0 structure
  • Name: 4',5'-Didehydro-5'-deoxyuridine
  • Chemical Name: 1-(5-Deoxy-β-D-erythro-pento-4-enofuranosyl)uracil
  • CAS Number: 14365-63-0
  • Molecular Formula: C9H10N2O5
  • Molecular Weight: 226.19
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2017-04-07 14:07:19
  • Modify Date: 2024-09-05 14:12:38
  • 4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 1-(5-Deoxy-β-D-erythro-pento-4-enofuranosyl)uracil
Synonyms 4',5'-didehydro-5'-deoxy-uridine
1-((2R,3R,4S)-3,4-dihydroxy-5-methylene-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
5'-deoxyuridin-4'-ene
1-(5-deoxy-β-D-erythro-pent-4-enofuranosyl)uracil
1-(5'-Deoxy-β-D-erythro-pent-4'-enofuranosyl)uracil
1-(5-Desoxy-β-D-erythro-Δ4-pentenofuransoyl)-uracil
Description 4',5'-Didehydro-5'-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Molecular Formula C9H10N2O5
Molecular Weight 226.19
Exact Mass 226.05900
PSA 104.55000
Precursor  0

DownStream  2