81732-46-9
81732-46-9 structure
- Name: Bambuterol Hydrochloride
- Chemical Name: bambuterol hydrochloride
- CAS Number: 81732-46-9
- Molecular Formula: C18H30ClN3O5
- Molecular Weight: 403.901
- Catalog: API Respiratory medication Asthma
- Create Date: 2018-07-18 21:37:11
- Modify Date: 2024-01-02 09:02:40
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Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor.
| Name | bambuterol hydrochloride |
|---|---|
| Synonyms |
(±)-Bambuterol hydrochloride
[3-[2-(tert-butylamino)-1-hydroxyethyl]-5-(dimethylcarbamoyloxy)phenyl] N,N-dimethylcarbamate,hydrochloride Bambuterol hydrochloride 5-[2-(tert-Butylamino)-1-hydroxyethyl]-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1) 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diyl bis(dimethylcarbamate) hydrochloride (1:1) Carbamic acid, N,N-dimethyl-, 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester, hydrochloride (1:1) 5-{1-Hydroxy-2-[(2-methyl-2-propanyl)amino]ethyl}-1,3-phenylene bis(dimethylcarbamate) hydrochloride (1:1) UNII:786Q84QZ3F MFCD03427293 Bambec Bambuterol (hydrochloride) |
| Description | Bambuterol Hcl is a long acting beta-adrenoceptor agonist (LABA) used in the treatment of asthma; it also is a prodrug of terbutaline.IC50 value:Target: beta-adrenoceptor agonistBambuterol is contraindicated in pregnancy and in people with seriously impaired liver function. It can be used by people with renal impairment, but dose adjustments are necessary. The adverse effect profile of bambuterol is similar to that of salbutamol, and may include fatigue, nausea, palpitations, headache, dizziness and tremor. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.154g/cm3 |
|---|---|
| Boiling Point | 500.9ºC at 760 mmHg |
| Melting Point | 222-224ºC |
| Molecular Formula | C18H30ClN3O5 |
| Molecular Weight | 403.901 |
| Flash Point | 256.7ºC |
| Exact Mass | 403.187408 |
| PSA | 91.34000 |
| LogP | 3.42180 |
| Index of Refraction | 1.533 |
| Storage condition | -20°C Freezer |
| Water Solubility | H2O: ~33 mg/mL, soluble |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |