103-26-4

103-26-4 structure

Name: Methyl cinnamate
Chemical Name: Methyl cinnamate
CAS Number: 103-26-4
Molecular Formula: C₁₀H₁₀O₂
Molecular Weight: 162.185
Catalog: Flavors and spices Synthetic spice Carboxylic acid and ester perfume Aromatic carboxylic acid ester
Create Date: 2018-05-28 08:00:00
Modify Date: 2024-01-03 16:59:04
Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway[1].

Name	Methyl cinnamate
Synonyms	METHYLCINNAMATE METHYL CINANMATE Cinnamic acid methylester E-3-phenyl-acrylic acid methyl ester (E)-cinnamic acid methyl ester TRANS-CINNAMIC ACID METHYL ESTER cinnamic acid methyl ester (2E)-3-Phenyl-2-propenoic acid methyl ester trans-3-Phenylacrylic Acid Methyl Ester METHYL-3-PHENYLPROPENOTE Methyl (2E)-3-phenylacrylate Methyl cinnamate METHYL CINNAMATE/CINNAMIC ACID METHYL ESTER EINECS 203-093-8 Methyl (E)-cinnamate 2-Propenoic acid, 3-phenyl-, methyl ester, (2E)- CINNAMICACIDMETHYLESTER MFCD00008458 Methyl trans-3-Phenylacrylate METHYL 3-PHENYLACRYLATE methyl (2E)-3-phenylprop-2-enoate METHYL CIMNAMATE NATURAL METHYL CINNAMYLATE Methyl trans-cinnamate FEMA 2698

Description	Methyl cinnamate (Methyl 3-phenylpropenoate), an active component of Zanthoxylum armatum, is a widely used natural flavor compound. Methyl cinnamate (Methyl 3-phenylpropenoate) possesses antimicrobial activity and is a tyrosinase inhibitor that can prevent food browning. Methyl cinnamate (Methyl 3-phenylpropenoate) has antiadipogenic activity through mechanisms mediated, in part, by the CaMKK2-AMPK signaling pathway[1].
Related Catalog	Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Research Areas >> Metabolic Disease Signaling Pathways >> Anti-infection >> Bacterial
In Vitro	In 3T3-L1 cell model, Methyl cinnamate (Methyl 3-phenylpropenoate) inhibits adipocyte differentiation by attenuating expression of the adipogenic transcription factors SREBP-1, PPARγ, and C/EBPα and the transcriptional activity of PPARγ. In addition, Methyl cinnamate (Methyl 3-phenylpropenoate) activates the CaMKK2−AMPK signaling cascade involved in the regulation of adipogenesis[1].
References	[1]. Chen YY, et al. Methyl cinnamate inhibits adipocyte differentiation via activation of the CaMKK2-AMPK pathwayin 3T3-L1 preadipocytes. J Agric Food Chem. 2012 Feb 1;60(4):955-63.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,849,1975

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,849,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83204 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 19 No. of Employees: 2695 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83204 No. of Facilities: 3528 (estimated) No. of Industries: 15 No. of Occupations: 36 No. of Employees: 57284 (estimated) No. of Female Employees: 39442 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	GE0190000
HS Code	2916399090

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%