Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Pinacidilmonohydrate
Price:
Purity: 99.0%
Stocking Period: 10 Day
Contact: Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Pinacidil hydrate
Price: ￥1508.0/100mg ￥6068.0/500mg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Pinacidil monohydrate (Pinacidil hydrate)
Price: $700.0/100mg $1400.0/250mg $2800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Pinacidil monohydrate (Pinacidil hydrate)
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Pinacidil
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

85371-64-8

85371-64-8 structure

85371-64-8 structure

Name: Pinacidil hydrate
Chemical Name: Pinacidil
CAS Number: 85371-64-8
Molecular Formula: C₁₃H₂₁N₅O
Molecular Weight: 263.34
Catalog: API Circulatory system medication Prevention and treatment of angina pectoris
Create Date: 2018-06-09 06:24:07
Modify Date: 2024-01-03 08:54:22
Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator.

Name	Pinacidil
Synonyms	Pinacidil (hydrate) Pinacidil . monohydrate 1-Cyano-3-(3,3-dimethylbutan-2-yl)-2-pyridin-4-ylguanidine hydrate (1:1) (+/-)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine MFCD00242745 Hndac GUANIDINE,N-CYANO-N'-4-PYRIDINYL-N''-(1,2,2-TRIMETHYLPROPYL)-, HYDRATE (1:1) Guanidine, N''-cyano-N-4-pyridinyl-N'-(1,2,2-trimethylpropyl)-, hydrate (1:1) Guanidine,N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-,monohydrate Pinacidil monohydrate EINECS 262-294-9 Pinacidil hydrate 1-Cyano-2-(3,3-dimethyl-2-butanyl)-3-(4-pyridinyl)guanidine hydrate (1:1)

Description	Pinacidil monohydrate, an antihypertensive drug, is a potassium channel activator.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel Research Areas >> Others
In Vitro	Pinacidil monohydrate is a potassium channel activator[1]. Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers"[2]. Pinacidil hydrate activates the ATP-modulated potassium channels of guinea pog bladder and heart with Ki values of 104 and 251 nM, respectively[3].
References	[1]. Buckle DR, et al. Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660. Pulm Pharmacol. 1993 Mar;6(1):77-86. [2]. Bareggi SR, et al. Pharmacodynamics and pharmacokinetics of pinacidil in normotensive volunteers after repeated doses of a new slow-release tablet formulation. Arzneimittelforschung. 1999 Jan;49(1):21-5. [3]. Gollasch M, et al. Pinacidil relaxes porcine and human coronary arteries by activating ATP-dependent potassium channels in smooth muscle cells. J Pharmacol Exp Ther. 1995 Nov;275(2):681-92.

Boiling Point	356.7ºC at 760 mmHg
Melting Point	164-165ºC
Molecular Formula	C₁₃H₂₁N₅O
Molecular Weight	263.34
Flash Point	169.5ºC
PSA	73.10000
LogP	2.94578
Storage condition	2-8℃
Water Solubility	ethanol: 14 mg/mL

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22;R36/37/38
Safety Phrases	S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2933399090

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%