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DC Chemicals Limited
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Dayang Chem (Hangzhou) Co., Ltd.
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515-64-0

515-64-0 structure

515-64-0 structure

Name: sulfisomidine
Chemical Name: sulfisomidine
CAS Number: 515-64-0
Molecular Formula: C₁₂H₁₄N₄O₂S
Molecular Weight: 278.330
Catalog: API Synthetic anti-infective drugs Sulfonamides and synergists
Create Date: 2018-06-20 10:13:28
Modify Date: 2024-01-03 18:11:10
Sulfisomidin is a sulfonamide antibacterial.

Name	sulfisomidine
Synonyms	Solfisomidina 4-amino-N-(2,6-dimethyl-pyrimidin-4-yl)-benzenesulfonamide Sulfaisodimidinum 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)benzenesulfonamide Sulfaisodimidine Sulfisomidin Sulfaisomidine 6-(Sulfanilamido)-2,4-dimethyl-1,3-diazine sulfisomidine Sulfadimetine benzenesulfonamide, 4-amino-N-(2,6-dimethyl-4-pyrimidinyl)- Sulfuisodimidine Sulphasomidine Sulfasomidine MFCD00010567 4-Amino-N-(2,6-dimethylpyrimidin-4-yl)benzenesulfonamide Sulfudimetine EINECS 208-204-3 Sulfamethin 2,6-dimethyl-4-pyrimidinyl sulphanilamide 6-(p-Aminophenylsulfonamido)-2,4-dimethylpyrimidine Domain

Description	Sulfisomidin is a sulfonamide antibacterial.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
In Vitro	Sulfisomidin (Sulfaisodimidine) is a short-acting antibacterial agent[1].
References	[1]. Bridges JW, et al. Species differences in the metabolism and excretion of sulphasomidine andsulphamethomidine. Biochem J. 1969 Jan;111(2):173-9.

Density	1.4±0.1 g/cm3
Boiling Point	480.7±55.0 °C at 760 mmHg
Melting Point	245ºC
Molecular Formula	C₁₂H₁₄N₄O₂S
Molecular Weight	278.330
Flash Point	244.5±31.5 °C
Exact Mass	278.083740
PSA	106.35000
LogP	-0.43
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.644
Storage condition	0-6°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WO9270000

CHEMICAL NAME :: Sulfanilamide, N(sup 1)-(2,6-dimethyl-4-pyrimidinyl)-

CAS REGISTRY NUMBER :: 515-64-0

BEILSTEIN REFERENCE NO. :: 0261305

LAST UPDATED :: 199707

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C12-H14-N4-O2-S

MOLECULAR WEIGHT :: 278.36

WISWESSER LINE NOTATION :: T6N CNJ B1 D1 FMSWR DZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 50 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,338,1953 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 6 gm/kg

SEX/DURATION :: female 9-14 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: SEIJBO Senten Ijo. Congenital Anomalies. (Nippon Senten Ijo Gakkai, c/o Kinki Daigaku Igakubu Kaibagaku Kyoshitsu, 380 Nishiyama, Sayama-cho, Mirami-Kawachi-gun, Osaka-fu, Japan) V.1-26, 1960-86. For publisher information, see CGANE7. Volume(issue)/page/year: 13,7,1973

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 2500 mg/kg

SEX/DURATION :: female 8-12 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

REFERENCE :: AKGIAO Akushcherstvo i Ginekologiya (Moscow). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1936- Volume(issue)/page/year: 43(12),10,1967

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	36/37/38
Safety Phrases	S26;S36
RIDADR	UN 3249
RTECS	WO9270000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2935009090

Precursor 9
461-98-3 847700-01-0 98-74-8 4472-45-1
63-74-1 121-60-8 112860-70-5 14001-65-1
667908-37-4
DownStream 1
3163-31-3

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%