Top Suppliers:I want be here
Related CAS#:
1306-06-5 68439-86-1
55575-17-2 12356-34-2
12167-74-7 2228481-50-1
2229684-10-8 2361645-67-0
2228926-00-7 2241140-87-2
2167240-07-3 876483-38-4
2229531-16-0 2138202-32-9
2172551-91-4

1306-06-5

1306-06-5 structure
1306-06-5 structure
  • Name: Hydroxylapatite
  • Chemical Name: Hydroxyapatite
  • CAS Number: 1306-06-5
  • Molecular Formula: Ca2HO5P
  • Molecular Weight: 502.311
  • Catalog: API Drugs that affect tissue metabolism
  • Create Date: 2018-02-05 08:00:00
  • Modify Date: 2024-01-02 19:15:49
  • Hydroxylapatite (Hydroxyapatite) is a naturally occurring calcium phosphate which is a major mineral component of bone and teeth bones. Nano-scale Hydroxylapatite particles are increasingly being used as carriers for controlled and targeted delivery of bioactive agents like drugs, proteins, and nucleic acids due to their high porosity, negative charge, and biodegradability [1].
Name Hydroxyapatite
Synonyms Durapatite
Hydroxylapatite
Calcium phosphate hydroxide,Durapatite,Hydroxylapatite
Hydroxyapatite
Monite
MFCD00010904
Calcium hydroxide phosphate (5:1:3)
EINECS 215-145-7
Description Hydroxylapatite (Hydroxyapatite) is a naturally occurring calcium phosphate which is a major mineral component of bone and teeth bones. Nano-scale Hydroxylapatite particles are increasingly being used as carriers for controlled and targeted delivery of bioactive agents like drugs, proteins, and nucleic acids due to their high porosity, negative charge, and biodegradability [1].
Related Catalog
References

[1]. Moumita Rakshit, et al. Hydroxyapatite Particles Induced Modulation of Collagen Expression and Secretion in Primary Human Dermal Fibroblasts. Int J Nanomedicine. 2020; 15: 4943–4956.

[2]. Yongjia Liu, et al. Hydroxyapatite-Bovine Serum Albumin-Paclitaxel Nanoparticles for Locoregional Treatment of Osteosarcoma. Adv Healthc Mater. 2020 Nov 9;e2000573.
Density 3.140 g/cm3
Boiling Point 158ºC at 760 mmHg
Melting Point 1100 °C(lit.)
Molecular Formula Ca2HO5P
Molecular Weight 502.311
Exact Mass 501.675964
PSA 119.12000
LogP 0.20920
Storage condition −20°C
Water Solubility H2O: 0.3 mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MY8434000
CHEMICAL NAME :
Hydroxylapatite (Ca5(OH)(PO4)3) (9CI)
CAS REGISTRY NUMBER :
1306-06-5
LAST UPDATED :
199806
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
Ca5-H-O13-P3
MOLECULAR WEIGHT :
502.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>25350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>19850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>99500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>25500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
200 mg/L
REFERENCE :
IJBBBQ Indian Journal of Biochemistry and Biophysics. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.8- 1971- Volume(issue)/page/year: 19,71,1982
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS MY8434000

Chemsrc provides CAS#:1306-06-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 1306-06-5 | Chemsrc address: https://www.chemsrc.com/en/baike/951432.html

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved