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163619-04-3

163619-04-3 structure
163619-04-3 structure
  • Name: Fmoc-D-Trp(Boc)-OH
  • Chemical Name: (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
  • CAS Number: 163619-04-3
  • Molecular Formula: C31H30N2O6
  • Molecular Weight: 526.580
  • Catalog: Biochemical Amino acids and their derivatives Tryptophan derivatives
  • Create Date: 2018-12-29 18:05:12
  • Modify Date: 2024-01-02 17:47:53
  • Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).

Name (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]indol-3-yl]propanoic acid
Synonyms 1-(tert-Butoxycarbonyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tryptophan
Nalpha-Fmoc-N(in)-Boc-D-tryptophan
AmbotzFAA1339
Fmoc-D-Trp(Boc)
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-D-tryptophan
D-Tryptophan, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
Fmoc-D-Trp(Boc)-OH
N|A-Fmoc-N(in)-Boc-D-tryptophan
Fmoc-L-Trp(Boc)-OH
MFCD00153367
(2R)-3-{1-[(tert-butoxy)carbonyl]-1H-indol-3-yl}-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid
Description Fmoc-D-Trp(Boc)-OH is a cleavable ADC linker that used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
Target

Cleavable

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Density 1.3±0.1 g/cm3
Melting Point 86 - 92ºC (Decomposes)
Molecular Formula C31H30N2O6
Molecular Weight 526.580
Exact Mass 526.210388
PSA 106.86000
LogP 7.05
Index of Refraction 1.632
Storage condition 2-8°C
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3