Shanghai Nianxing Industrial Co., Ltd
China
Product Name: ethynylpyrene
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Purity: 98.0%
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DC Chemicals Limited
China
Product Name: 1-ethynylpyrene
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Purity: 98.0%
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-ETHYNYLPYRENE
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Purity: 98.0%
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34993-56-1

34993-56-1 structure

34993-56-1 structure

Name: ethynylpyrene
Chemical Name: 1-ethynylpyrene
CAS Number: 34993-56-1
Molecular Formula: C₁₈H₁₀
Molecular Weight: 226.272
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2018-03-28 08:00:00
Modify Date: 2024-01-11 13:47:39
1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].

Name	1-ethynylpyrene
Synonyms	8-ethynylpyrene 1-Ethynylpyrene ethynylpyrene Pyrene, 1-ethynyl- 1-Ethynyl Pyrene Pyrene,1-ethynyl MFCD02093933 3-pyrenylacetylene 1-pyrenylacetylene pyrene-1-acetylene ethynyl pyrene

Description	1-Ethynylpyrene is an aryl acetylenic inhibitor of cytochromes P450 1A1, 1A2, and 2B1 with IC50s of 0.18, 0.32, and 0.04 μM, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
In Vitro	1-Ethynylpyrene exhibits activity against P450 1A2, and 2B1 with Kis of 0.32 and 0.04 μM, respectively[1].
References	[1]. Naijue Zhu, et al. Ethynyl and Propynylpyrene Inhibitors of Cytochrome P450. J Chem Crystallogr. 2010 Apr 1;40(4):343-352.

Density	1.2±0.1 g/cm3
Boiling Point	410.6±14.0 °C at 760 mmHg
Melting Point	113-115ºC
Molecular Formula	C₁₈H₁₀
Molecular Weight	226.272
Flash Point	194.9±14.2 °C
Exact Mass	226.078247
LogP	5.35
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.807

Safety Phrases	S22-S24/25
HS Code	2902909090

Precursor 10
253271-87-3 1714-29-0 884307-53-3 215451-63-1
1392406-87-9 3029-19-4 90965-06-3 34244-15-0
115-19-5 3264-21-9
DownStream 2
23975-18-0 27208-37-3

HS Code	2902909090
Summary	2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%