Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Quinalizarin
Price:
Purity: 95.0%
Stocking Period: 10 Day
Contact: Yang

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Quinalizarin
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai

DC Chemicals Limited
China
Product Name: Quinalizarin
Price: $350.0/25mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,2,5,8-Tetrahydroxyanthraquinone
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

81-61-8

81-61-8 structure

Name: Quinalizarin
Chemical Name: quinalizarin
CAS Number: 81-61-8
Molecular Formula: C₁₄H₈O₆
Molecular Weight: 272.210
Catalog: Signaling Pathways Cell Cycle/DNA Damage Casein Kinase
Create Date: 2018-09-17 00:31:08
Modify Date: 2024-01-12 10:02:13
Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1].

Name	quinalizarin
Synonyms	1,2,5,8-tetrahydroxy-9,10-anthracenedione Alizarinbordeaux 9,10-Anthracenedione, 1,2,5,8-tetrahydroxy- MFCD00001205 9,10-Anthracenedione,1,2,5,8-tetrahydroxy Alizarine Bordeaux B 1,2,5,8-Tetrahydroxy-9,10-anthraquinone Mordant Violet 26 Khinalizarin Alizarine Bordeaux C.I. Mordant Violet 26 Alizarin bordeaux B 1,2,5,8-tetrahydroxyanthracene-9,10-dione Quinalizarin 1,2,5,8-tetrahydroxyanthraquinone EINECS 201-366-6

Description	Quinalizarin is a potent, selective and cell-permeable protein kinase CK2 inhibitor with an Ki of ~50 nM and an IC50 of 110 nM. Quinalizarin can induce apoptosis of certain cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Casein Kinase Signaling Pathways >> Stem Cell/Wnt >> Casein Kinase
Target	CK2:~50 nM (Ki) CK2:110 nM (IC50)
References	[1]. Cozza G, et al. Quinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2. Biochem J. 2009;421(3):387-395. Published 2009 Jul 15.

Density	1.8±0.1 g/cm3
Boiling Point	517.1±45.0 °C at 760 mmHg
Melting Point	99 °C
Molecular Formula	C₁₄H₈O₆
Molecular Weight	272.210
Flash Point	280.6±25.2 °C
Exact Mass	272.032074
PSA	115.06000
LogP	5.18
Vapour Pressure	0.0±1.4 mmHg at 25°C
Index of Refraction	1.815
Storage condition	room temp

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CB8069900

CHEMICAL NAME :: Anthraquinone, 1,2,5,8-tetrahydroxy-

CAS REGISTRY NUMBER :: 81-61-8

BEILSTEIN REFERENCE NO. :: 1889617

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C14-H8-O6

MOLECULAR WEIGHT :: 272.22

WISWESSER LINE NOTATION :: L C666 BV IVJ DQ EQ KQ NQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 50 ug/plate

REFERENCE :: BCSTB5 Biochemical Society Transactions. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1973- Volume(issue)/page/year: 5,1489,1977

Symbol	GHS07, GHS09
Signal Word	Warning
Hazard Statements	H302-H400
Precautionary Statements	P273
Hazard Codes	Xn,N
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	UN 3077 9 / PGIII

72-48-0

81-61-8

Literature: DE60855 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 198 Journal fuer Praktische Chemie (Leipzig), , vol. <2>43, p. 239 Chemische Berichte, , vol. 23, p. 3739 Justus Liebigs Annalen der Chemie, , vol. 349, p. 205

518-90-1

123-31-9

81-61-8

Literature: Justus Liebigs Annalen der Chemie, , vol. 240, p. 301

14597-12-7

120-80-9

81-61-8

Literature: Journal of Organic Chemistry, , vol. 6, p. 732,747 Journal of Organic Chemistry, , vol. 7, p. 63,66

81-64-1

81-61-8

Literature: DE63693 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 3, p. 201 Journal fuer Praktische Chemie (Leipzig), , vol. <2>43, p. 249

81-64-1

7664-93-9

13460-50-9

81-61-8

Literature: DE161026 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 8, p. 256

Precursor 8
72-48-0 518-90-1 123-31-9 14597-12-7
120-80-9 81-64-1 7664-93-9 13460-50-9
DownStream 4
69837-16-7 61169-36-6 6373-25-7 5413-65-0

1158522-08-7	2639462-46-5
940364-43-2	134104-43-1
131615-57-1	18725-24-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4