73912-52-4
73912-52-4 structure
- Name: MS 15203
- Chemical Name: chembrdg-bb 5186719
- CAS Number: 73912-52-4
- Molecular Formula: C12H11NO5
- Molecular Weight: 249.21900
- Catalog: Research Areas Metabolic Disease
- Create Date: 2017-12-12 05:43:53
- Modify Date: 2024-01-03 12:50:53
-
MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1].
| Name | chembrdg-bb 5186719 |
|---|---|
| Synonyms | MFCD00434754 |
| Description | MS15203 is a potent and selective GPR171 agonist. MS15203 increases food intake and body weight. MS15203 increases neuronal activity. MS15203 significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. |
|---|---|
| Related Catalog | |
| In Vitro | MS15203 (MS0015203) dose-dependently increases [[35]S]GTPγS binding and inhibits adenylyl cyclase activity in rat hypothalamic membranes[1]. |
| In Vivo | MS15203 (MS0015203) (3 mg/kg; i.p.) causes an increase in neuronal activity within cells containing GPR171 in the PVN[1]. .MS15203 (3 mg/kg; i.p.) significantly increases food intake at 4 and 8 hours[1]. MS15203 (3 mg/kg; i.p.) significantly increases the abundance of the mRNAs encoding proSAAS, NPY, AgRP[1]. |
| References |
| Density | 1.42g/cm3 |
|---|---|
| Boiling Point | 561.3ºC at 760 mmHg |
| Molecular Formula | C12H11NO5 |
| Molecular Weight | 249.21900 |
| Flash Point | 293.2ºC |
| Exact Mass | 249.06400 |
| PSA | 103.70000 |
| LogP | 1.67060 |
| Index of Refraction | 1.639 |
| HS Code | 2924199090 |
|---|
|
~82%
73912-52-4 |
| Literature: Ezhova, N. M.; Kulina, E. A.; Kuznetsova, N. N. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1980 , vol. 29, # 2 p. 267 - 269 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1980 , # 2 p. 352 - 354 |
| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |