5579-13-5

5579-13-5 structure
5579-13-5 structure

Name N-carbamoyl-2-ethyl-3-methylpentanamide
Synonyms CAPURIDE
McN-X-94
2-Ethyl-3-methylpentanoyl-harnstoff
1-(2-ethyl-3-methyl-pentanoyl)-urea
(2-ethyl-3-methyl-valeryl)-urea
Pacinox
(Ethyl-sec-butylacetyl)urea
(2-Aethyl-3-methyl-valeryl)-harnstoff
mcn-x 9
Capurid
sec.Butylethylacetylharnstoff
Description Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1].
Related Catalog
In Vivo Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats[2]. Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2]. Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2]. Animal Model: Electrically (MES) and chemically (scMet) induced seizures in rats[2] Dosage: 38-107 mg/kg Administration: Oral administration (p.o.) Result: ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model).
Density 1.009g/cm3
Molecular Formula C9H18N2O2
Molecular Weight 186.25100
Exact Mass 186.13700
PSA 72.19000
LogP 2.34480
Index of Refraction 1.463

~%

5579-13-5 structure

5579-13-5

Literature: Volwiler; Tabern Journal of the American Chemical Society, 1936 , vol. 58, p. 1352 Chem. Zentralbl., 1935 , vol. 106, # I p. 1271 Full Text View citing articles Show Details Abbott Labor. Patent: US1969828 , 1931 ;

~%

5579-13-5 structure

5579-13-5

Literature: Kaufmann, Dan; Bialer, Meir; Shimshoni, Jakob Avi; Devor, Marshall; Yagen, Boris Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7236 - 7248
Precursor  2

DownStream  0