Name | N-carbamoyl-2-ethyl-3-methylpentanamide |
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Synonyms |
CAPURIDE
McN-X-94 2-Ethyl-3-methylpentanoyl-harnstoff 1-(2-ethyl-3-methyl-pentanoyl)-urea (2-ethyl-3-methyl-valeryl)-urea Pacinox (Ethyl-sec-butylacetyl)urea (2-Aethyl-3-methyl-valeryl)-harnstoff mcn-x 9 Capurid sec.Butylethylacetylharnstoff |
Description | Capuride is an orally active sedative agent. Capuride has anticonvulsant activity[1]. |
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Related Catalog | |
In Vivo | Capuride (VPA, 38-107 mg/kg p.o.) shows anticonvulsant activity in MES and scMet induced seizures rats[2]. Capuride (p.o., rats) shows neurotoxicity with an ED50 of 232 mg/kg[2]. Capuride (49-71 mg/kg, i.p.) shows anticonvulsant activity in 6 Hz Psychomotor seizure mice[2]. Animal Model: Electrically (MES) and chemically (scMet) induced seizures in rats[2] Dosage: 38-107 mg/kg Administration: Oral administration (p.o.) Result: ED50s: 54 mg/kg (MES model), 77 mg/kg (scMet model). |
Density | 1.009g/cm3 |
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Molecular Formula | C9H18N2O2 |
Molecular Weight | 186.25100 |
Exact Mass | 186.13700 |
PSA | 72.19000 |
LogP | 2.34480 |
Index of Refraction | 1.463 |
~% 5579-13-5 |
Literature: Volwiler; Tabern Journal of the American Chemical Society, 1936 , vol. 58, p. 1352 Chem. Zentralbl., 1935 , vol. 106, # I p. 1271 Full Text View citing articles Show Details Abbott Labor. Patent: US1969828 , 1931 ; |
~% 5579-13-5 |
Literature: Kaufmann, Dan; Bialer, Meir; Shimshoni, Jakob Avi; Devor, Marshall; Yagen, Boris Journal of Medicinal Chemistry, 2009 , vol. 52, # 22 p. 7236 - 7248 |
Precursor 2 | |
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DownStream 0 |