84364-89-6
84364-89-6 structure
- Name: Fructose 2,6-biphosphate sodium salt
- Chemical Name: D-Fructose 2,6-diphosphate sodium salt
- CAS Number: 84364-89-6
- Molecular Formula: C6H14O12P2.xNa
- Molecular Weight: 362.098
- Catalog: Research Areas Metabolic Disease
- Create Date: 2018-09-22 12:07:18
- Modify Date: 2024-01-03 12:21:24
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Fructose 2,6-biphosphate sodium salt is a potent stimulator of 6-Phosphofructo-1-kinase (PFK-1) and also inhibits Fructose-1,6-Bisphosphatase[1].
| Name | D-Fructose 2,6-diphosphate sodium salt |
|---|---|
| Synonyms |
Sodium 2-O-(hydroxyphosphinato)-6-O-phosphono-β-D-fructofuranose
D-(-)-fructose D-Arabino-hexulose D-Fructose 2,6-bisphosphate sodium salt β-D-Fructofuranose, 2,6-bis(dihydrogen phosphate), sodium salt (1:1) D-fructofuranose |
| Description | Fructose 2,6-biphosphate sodium salt is a potent stimulator of 6-Phosphofructo-1-kinase (PFK-1) and also inhibits Fructose-1,6-Bisphosphatase[1]. |
|---|---|
| Related Catalog | |
| Target |
PFK-1, Fructose-1,6-Bisphosphatase[1] |
| In Vitro | A concentration-dependent inhibition of fructose-1,6-Bisphosphatase by Fructose 2,6-bisphosphate is observed. Another characteristic of this inhibition is that it changes the saturation curve from hyperbolic to sigmoidal. This effect is clearly apparent at 25 pM Fructose 2,6-bisphosphate. It appears that the inhibitory actions of Fructose 2,6-bisphosphate and of AMP are synergistic. Indeed, at 10 pM fructose 1,6-bisphosphate, the addition of AMP alone causes a 35% inhibition but, it increases the inhibition by 1 pM Fructose 2,6-bisphosphate from 20% to 80%[1]. |
| References |
| Molecular Formula | C6H14O12P2.xNa |
|---|---|
| Molecular Weight | 362.098 |
| Exact Mass | 361.977997 |
| PSA | 225.89000 |
| Risk Phrases | 23/24/25-36/37/38-39/23/24/25 |
|---|---|
| Safety Phrases | 26-36/37-45 |