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121305-26-8

121305-26-8 structure
121305-26-8 structure
  • Name: H-Leu-Pro-Pro-OH
  • Chemical Name: (2S)-1-[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
  • CAS Number: 121305-26-8
  • Molecular Formula: C16H27N3O4
  • Molecular Weight: 325.40300
  • Catalog: Research Areas Cardiovascular Disease
  • Create Date: 2018-12-03 08:39:04
  • Modify Date: 2024-02-04 11:04:12
  • LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension[1].

Name (2S)-1-[(2S)-1-[(2S)-2-amino-4-methylpentanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Synonyms 1-(1-L-Leucyl-L-prolyl)-L-proline
L-Proline,1-(1-L-leucyl-L-prolyl)
Description LPP Tripeptide is a blood pressure lowering tripeptides. LPP Tripeptide can be used for research of hypertension[1].
Related Catalog
References

[1]. van der Pijl PC, et al. Pharmacokinetics of proline-rich tripeptides in the pig. Peptides. 2008 Dec;29(12):2196-202.  

Density 1.247g/cm3
Boiling Point 572.6ºC at 760mmHg
Molecular Formula C16H27N3O4
Molecular Weight 325.40300
Flash Point 300.1ºC
Exact Mass 325.20000
PSA 103.94000
LogP 1.00250
Vapour Pressure 1.33E-14mmHg at 25°C
Index of Refraction 1.556

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TW3675000
CHEMICAL NAME :
L-Proline, 1-(1-L-leucyl-L-prolyl)-
CAS REGISTRY NUMBER :
121305-26-8
LAST UPDATED :
199506
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H27-N3-O4
MOLECULAR WEIGHT :
325.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #90-240027