35638-19-8

35638-19-8 structure

Name: 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane
Chemical Name: ys 1033
CAS Number: 35638-19-8
Molecular Formula: C₁₇H₂₈O₁₂
Molecular Weight: 424.39700
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2016-03-21 16:06:12
Modify Date: 2024-03-31 22:36:57
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	ys 1033
Synonyms	MFCD08669605

Description	1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562