1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane

Modify Date: 2024-03-31 22:36:57

1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane Structure
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane structure
Common Name 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane
CAS Number 35638-19-8 Molecular Weight 424.39700
Density 1.355g/cm3 Boiling Point 710.3ºC at 760mmHg
Molecular Formula C17H28O12 Melting Point N/A
MSDS N/A Flash Point 248.8ºC

 Use of 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane


1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name ys 1033
Synonym More Synonyms

  Biological Activity

Description 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.355g/cm3
Boiling Point 710.3ºC at 760mmHg
Molecular Formula C17H28O12
Molecular Weight 424.39700
Flash Point 248.8ºC
Exact Mass 424.15800
PSA 186.12000
Index of Refraction 1.512

 Synonyms

MFCD08669605
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