1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane

Modify Date: 2024-03-31 22:36:57

1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane structure	Common Name	1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane
	CAS Number	35638-19-8	Molecular Weight	424.39700
	Density	1.355g/cm3	Boiling Point	710.3ºC at 760mmHg
	Molecular Formula	C₁₇H₂₈O₁₂	Melting Point	N/A
	MSDS	N/A	Flash Point	248.8ºC

Use of 1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane

1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	ys 1033
Synonym	More Synonyms

Description	1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density	1.355g/cm3
Boiling Point	710.3ºC at 760mmHg
Molecular Formula	C₁₇H₂₈O₁₂
Molecular Weight	424.39700
Flash Point	248.8ºC
Exact Mass	424.15800
PSA	186.12000
Index of Refraction	1.512

MFCD08669605