94470-67-4
94470-67-4 structure
- Name: Cromakalim
- Chemical Name: (±)-Cromakalim
- CAS Number: 94470-67-4
- Molecular Formula: C16H20N2O3S
- Molecular Weight: 286.33
- Catalog: Signaling Pathways Membrane Transporter/Ion Channel Potassium Channel
- Create Date: 2018-08-10 10:58:31
- Modify Date: 2024-01-01 22:49:02
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Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1].
| Name | (±)-Cromakalim |
|---|---|
| Synonyms |
(3R,4S)-3-Hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-chromanecarbonitrile
(3R,4S)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)-3,4-dihydro-2H-chromene-6-carbonitrile 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, (3R,4S)- (+)-Cromakalim |
| Description | Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 482.3±45.0 °C at 760 mmHg |
| Melting Point | 242-244ºC |
| Molecular Formula | C16H20N2O3S |
| Molecular Weight | 286.33 |
| Flash Point | 245.5±28.7 °C |
| Exact Mass | 286.131744 |
| PSA | 73.56000 |
| LogP | 1.27 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.615 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| Precursor 0 | |
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| DownStream 3 | |
