319460-94-1

319460-94-1 structure

Name: AG-13958
Chemical Name: N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amin o)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
CAS Number: 319460-94-1
Molecular Formula: C₂₆H₂₂FN₇O
Molecular Weight: 467.498
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
Create Date: 2018-12-23 07:00:23
Modify Date: 2024-04-05 16:39:13
AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].

Name	N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amin o)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
Synonyms	N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amino)phenyl]-1,4-dimethyl-1H-pyrazole-5-carboxamide 2,5-dimethyl-2H-pyrazole-3-carboxylic acid {2-fluoro-5-[3-((E)-2-pyridin-2-yl-vinyl)-1H-indazol-6-ylamino]-phenyl}-amide 1H-Pyrazole-5-carboxamide, N-[2-fluoro-5-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl- 6-[N-(3-((1,3-dimethyl-1H-pyrazol-5-yl)carboxamido)-4-fluoro-phenyl)amino]-3-(E)-[2-(pyridin-2-yl)ethenyl]-1H-indazole N-[2-Fluoro-5-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}amino)phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide 6-[methyl(phenylsulfonyl)amino]-hexanoic acid 1H-Pyrazole-5-carboxamide, N-[2-fluoro-5-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,4-dimethyl- 6-(benzenesulfonyl-methyl-amino)-hexanoic acid 6-(Methyl(phenylsulphonyl)amino)hexanoic acid 6-(Benzolsulfonyl-methyl-amino)-hexansaeure

Description	AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	VEGFR
References	[1]. M.B. Kosa, et al. Ocular and Systemic Pharmacokinetics of AG-013958 With Sub-Tenon Administration To Cynomologus Monkeys. Investigative Ophthalmology & Visual Science May 2005, Vol.46, 5379.