Name | (3β)-27-{[(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoyl]oxy}-3-hydroxy olean-12-en-28-oic acid |
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Synonyms |
(3β)-27-{[(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoyl]oxy}-3-hydroxyolean-12-en-28-oic acid
Myriceron caffeoyl ester Myriceric acid B myriceric acid A Olean-12-en-28-oic acid, 27-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3-hydroxy-, (3β)- |
Description | Myriceric acid B is a potent HIV-1 entry inhibitor targeting gp41. Myriceric acid B is an antitumor agent[1][2]. |
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Related Catalog | |
Target |
HIV-1:8.3±0.2 μg/mL (IC50, infection of HIV-1 Env pseudovirus) |
In Vitro | Myriceric acid B (0-30 μM; 72 h) 对肿瘤细胞有强烈的细胞毒性[1]。 Myriceric acid B 抑制 HIV-1 Env 假病毒感染的 IC50 为 8.3±0.2 mg/L[2]。 Cell Cytotoxicity Assay[1] Cell Line: A549, SK-OV-3, SK-MEL-2 and Bt549 Concentration: 0-30 μM Incubation Time: 72 h Result: Exhibited potent cytotoxicity against all of the tumor cell lines tested, with IC50s of 5.7±0.3, 9.8±0.5, 6.0±0.7 and 5.8±0.4 μM against A549, SK-OV-3, SK-MEL-2 and Bt549, respectively. |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 752.3±60.0 °C at 760 mmHg |
Molecular Formula | C39H54O7 |
Molecular Weight | 634.842 |
Flash Point | 227.0±26.4 °C |
Exact Mass | 634.386963 |
PSA | 124.29000 |
LogP | 9.07 |
Vapour Pressure | 0.0±2.6 mmHg at 25°C |
Index of Refraction | 1.610 |
Hazard Codes | Xi |
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