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55-52-7

55-52-7 structure
55-52-7 structure
  • Name: Pheniprazine
  • Chemical Name: 1-phenylpropan-2-ylhydrazine
  • CAS Number: 55-52-7
  • Molecular Formula: C9H14N2
  • Molecular Weight: 150.22100
  • Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
  • Create Date: 2018-06-01 08:00:00
  • Modify Date: 2024-01-09 15:24:22
  • Pheniprazine is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression[1].
Name 1-phenylpropan-2-ylhydrazine
Synonyms Dicatron
Phenizine
2-Hydrazinopropylbenzene
Pheniprazine
Catron
fenizin
Fenilisopropilidrazina
Description Pheniprazine is a potent and long acting inhibitor of monoamine oxidase. Pheniprazine has the potential for the research of depression[1].
Related Catalog
Target

monoamine oxidase[1]

References

[1]. HORITA A. beta-Phenylisopropylhydrazine, a potent and long acting monoamine oxidase inhibitor. J Pharmacol Exp Ther.

[2]. Stein, Larry, et al. Accelerated recovery from reserpine depression by monoamine oxidase inhibitors.
Density 0.99g/cm3
Boiling Point 287.1ºC at 760mmHg
Molecular Formula C9H14N2
Molecular Weight 150.22100
Flash Point 148ºC
Exact Mass 150.11600
PSA 38.05000
LogP 2.17210
Index of Refraction 1.539

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MV7350000
CHEMICAL NAME :
Hydrazine, (alpha-methylphenethyl)-
CAS REGISTRY NUMBER :
55-52-7
LAST UPDATED :
199706
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C9-H14-N2
MOLECULAR WEIGHT :
150.25
WISWESSER LINE NOTATION :
ZMY1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - man
DOSE/DURATION :
117 mg/kg/2.5Y
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - visual field changes Sense Organs and Special Senses (Eye) - effect, not otherwise specified
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
34 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
45 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
44 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
121 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
48 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
95 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12100 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - nausea or vomiting
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
30 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Gastrointestinal - changes in structure or function of salivary glands Gastrointestinal - nausea or vomiting

MUTATION DATA

TYPE OF TEST :
Mutation test systems - not otherwise specified
TEST SYSTEM :
Bacteria - Bacillus subtilis
DOSE/DURATION :
10 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 5,343,1968
HS Code 2928000090
5171-99-3 structure

5171-99-3

~%

55-52-7 structure

55-52-7

Literature: Journal of the American Chemical Society, , vol. 81, p. 2805,2810, 2813
103-79-7 structure

103-79-7

~%

55-52-7 structure

55-52-7

Literature: Journal of Medicinal and Pharmaceutical Chemistry, , vol. 5, # 2 p. 221 - 230
100-39-0 structure

100-39-0

~%

55-52-7 structure

55-52-7

Literature: Journal of the Chemical Society, Chemical Communications, , # 2 p. 176 - 178
2114-39-8 structure

2114-39-8

~%

55-52-7 structure

55-52-7

Literature: Journal of Medicinal Chemistry, , vol. 54, # 8 p. 2610 - 2626
19852-13-2 structure

19852-13-2

~%

55-52-7 structure

55-52-7

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 30, p. 2754 - 2756,2736 - 2738
637-50-3 structure

637-50-3

~%

55-52-7 structure

55-52-7

Literature: Chemische Berichte, , vol. 98, p. 904 - 911
HS Code 2928000090
Summary 2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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