144773-26-2

144773-26-2 structure

Name: cyclophostin
Chemical Name: (3R,8aR)-3-methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-furo[3,4-e][1,3,2]dioxaphosphepin-6-one
CAS Number: 144773-26-2
Molecular Formula: C₈H₁₁O₆P
Molecular Weight: 234.14300
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2017-12-12 10:45:40
Modify Date: 2024-01-10 19:29:16
Cyclophostin is an acetylcholinesterase (AChE) inhibitor with IC50 values of 45, 0.76 and 1.3 nM for humans and two different insects, respectively[1].

Name	(3R,8aR)-3-methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-furo[3,4-e][1,3,2]dioxaphosphepin-6-one
Synonyms	Cyclophostin Rac-Cyclophostin 1H,6H-Furo(3,4-e)(1,3,2)dioxaphosphepin-6-one,8,8a-dihydro-3-methoxy-5-methyl-,3-oxide,(3R-cis)

Description	Cyclophostin is an acetylcholinesterase (AChE) inhibitor with IC50 values of 45, 0.76 and 1.3 nM for humans and two different insects, respectively[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
References	[1]. Spilling CD. The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds. Molecules. 2019 Jul 16;24(14):2579.