cyclophostin

Modify Date: 2024-01-10 19:29:16

cyclophostin Structure
cyclophostin structure
Common Name cyclophostin
CAS Number 144773-26-2 Molecular Weight 234.14300
Density 1.41g/cm3 Boiling Point 338.1ºC at 760mmHg
Molecular Formula C8H11O6P Melting Point N/A
MSDS N/A Flash Point 172ºC

 Use of cyclophostin


Cyclophostin is an acetylcholinesterase (AChE) inhibitor with IC50 values of 45, 0.76 and 1.3 nM for humans and two different insects, respectively[1].

 Names

Name (3R,8aR)-3-methoxy-5-methyl-3-oxo-8,8a-dihydro-1H-furo[3,4-e][1,3,2]dioxaphosphepin-6-one
Synonym More Synonyms

 cyclophostin Biological Activity

Description Cyclophostin is an acetylcholinesterase (AChE) inhibitor with IC50 values of 45, 0.76 and 1.3 nM for humans and two different insects, respectively[1].
Related Catalog
References

[1]. Spilling CD. The Chemistry and Biology of Cyclophostin, the Cyclipostins and Related Compounds. Molecules. 2019 Jul 16;24(14):2579.  

 Chemical & Physical Properties

Density 1.41g/cm3
Boiling Point 338.1ºC at 760mmHg
Molecular Formula C8H11O6P
Molecular Weight 234.14300
Flash Point 172ºC
Exact Mass 234.02900
PSA 80.87000
LogP 1.23470
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.495

 Synonyms

Cyclophostin
Rac-Cyclophostin
1H,6H-Furo(3,4-e)(1,3,2)dioxaphosphepin-6-one,8,8a-dihydro-3-methoxy-5-methyl-,3-oxide,(3R-cis)
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