Name | Fibrinopeptide A |
---|---|
Synonyms |
fibrinopeptide a, human
MFCD00076437 ADSGEGDFLAEGGGVR |
Description | Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain. |
---|---|
Related Catalog | |
In Vitro | The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which binds to the central region of fibrinogen and catalyzes cleavage of the 2 short peptides, the 16-residue fibrinopeptide A (FpA) and the 14-residue fibrinopeptide B (FpB), located at the NH2-termini of the Aα and Bβ chains, respectively[1]. |
In Vivo | Fibrinopeptide A (FPA) is a small polypeptide cleaved from fibrinogen by thrombin, has a short half-life, and is considered a sensitive biochemical marker of thrombin activity, fibrin generation, and ongoing thrombosis[2]. |
References |
Density | 1.53 g/cm3 |
---|---|
Molecular Formula | C63H97N19O26 |
Molecular Weight | 1536.56000 |
Exact Mass | 1535.69000 |
PSA | 731.15000 |
Storage condition | −20°C |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |