192314-93-5

192314-93-5 structure

Name: Iclaprim
Chemical Name: iclaprim
CAS Number: 192314-93-5
Molecular Formula: C₁₉H₂₂N₄O₃
Molecular Weight: 354.403
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-12-25 10:48:01
Modify Date: 2024-01-06 12:18:37
Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 mg/mL.

Name	iclaprim
Synonyms	Iclaprim 2,4-Pyrimidinediamine, 5-[(2-cyclopropyl-7,8-dimethoxy-2H-1-benzopyran-5-yl)methyl]- 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine 5-[(2-Cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl)methyl]-2,4-pyrimidinediamine

Description	Iclaprim is a new selective bacterial Dihydrofolate inhibitor, which can inhibit the growth of S. aureus (MRSA) with an MIC90 of 0.06 mg/mL.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
Target	Dihydrofolate[1]
References	[1]. Schneider P, et al. Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria. Bioorg Med Chem Lett. 2003 Dec 1;13(23):4217-21.