Entadamide A

Modify Date: 2024-01-15 19:03:24

Entadamide A Structure
Entadamide A structure
Common Name Entadamide A
CAS Number 100477-88-1 Molecular Weight 161.22
Density 1.163g/cm3 Boiling Point 379.7ºC at 760mmHg
Molecular Formula C6H11NO2S Melting Point N/A
MSDS N/A Flash Point 183.4ºC

 Use of Entadamide A


Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

 Names

Name (E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide
Synonym More Synonyms

 Entadamide A Biological Activity

Description Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].
Related Catalog
References

[1]. Nzowa LK, et al. Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia. 2013 Jun;87:37-42.  

 Chemical & Physical Properties

Density 1.163g/cm3
Boiling Point 379.7ºC at 760mmHg
Molecular Formula C6H11NO2S
Molecular Weight 161.22
Flash Point 183.4ºC
Exact Mass 161.05100
PSA 74.63000
LogP 0.36250
Vapour Pressure 2.53E-07mmHg at 25°C
Index of Refraction 1.533

 Synonyms

entadamide A
2-Propenamide,n-(2-hydroxyethyl)-3-(methylthio)-,(E)
N-(2-Hydroxyethyl)-3-methylthiopropenamide