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100477-88-1

100477-88-1 structure
100477-88-1 structure
  • Name: Entadamide A
  • Chemical Name: (E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide
  • CAS Number: 100477-88-1
  • Molecular Formula: C6H11NO2S
  • Molecular Weight: 161.22
  • Catalog: Research Areas Infection
  • Create Date: 2017-09-21 20:52:37
  • Modify Date: 2024-01-15 19:03:24
  • Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].

Name (E)-N-(2-hydroxyethyl)-3-methylsulfanylprop-2-enamide
Synonyms entadamide A
2-Propenamide,n-(2-hydroxyethyl)-3-(methylthio)-,(E)
N-(2-Hydroxyethyl)-3-methylthiopropenamide
Description Entadamide A (compound 1) is a tryptophan derivative. Entadamide A prevents tryptophan depletion by inhibiting indoleamine 2, 3-dioxygenase (IDO), thereby inhibiting HIV replication. Entadamide A can be used in drug and neuropsychiatric studies of redesivir [1].
Related Catalog
References

[1]. Nzowa LK, et al. Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity. Fitoterapia. 2013 Jun;87:37-42.  

Density 1.163g/cm3
Boiling Point 379.7ºC at 760mmHg
Molecular Formula C6H11NO2S
Molecular Weight 161.22
Flash Point 183.4ºC
Exact Mass 161.05100
PSA 74.63000
LogP 0.36250
Vapour Pressure 2.53E-07mmHg at 25°C
Index of Refraction 1.533