Tubulin polymerization-IN-38

Modify Date: 2024-01-12 11:45:32

Tubulin polymerization-IN-38 structure	Common Name	Tubulin polymerization-IN-38
	CAS Number	1005192-31-3	Molecular Weight	638.82
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₅₀N₄O₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tubulin polymerization-IN-38

Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1].

Name	Tubulin polymerization-IN-38

Description	Tubulin polymerization-IN-38 a Tubulysin (HY-128914) analogue, is a potent anticancer agent. Tubulin polymerization-IN-38 inhibits tubulin polymerisation and thereby inducing apoptosis. Tubulin polymerization-IN-38 has cytotoxicity against cancer cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target	Tubulin polymerisation[1]
In Vitro	Tubulin polymerization-IN-38 (example 5) exhibits cytotoxicity against L929, SW-480 and KB-3-1 with IC50s of 2.2 ng/mL, 0.35 ng/mL and 1.5 ng/mL, respectively[1].
References	[1]. Jonathan A. Ellman, et al. Tubulysin d analogues. WO2009012958A2.

Molecular Formula	C₃₁H₅₀N₄O₈S
Molecular Weight	638.82

Tubulin polymerization-IN-38

Use of Tubulin polymerization-IN-38

Names

Tubulin polymerization-IN-38 Biological Activity

Chemical & Physical Properties