GSK-1521498

Modify Date: 2024-01-02 17:58:25

GSK-1521498 structure	Common Name	GSK-1521498
	CAS Number	1007573-18-3	Molecular Weight	326.34300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₄H₂₀F₂N₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of GSK-1521498

GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].

Name	N-[[2,6-difluoro-3-(1H-1,2,4-triazol-5-yl)phenyl]methyl]-2,3-dihydro-1H-inden-2-amine
Synonym	More Synonyms

Description	GSK1521498 free base is a potent and selective μ-opioid receptor (MOR) antagonist. GSK1521498 free base is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
Target	μ-opioid receptor[1]
References	[1]. Giuliano C, et al. The Novel μ-Opioid Receptor Antagonist GSK1521498 Decreases Both Alcohol Seeking and Drinking: Evidence from a New Preclinical Model of Alcohol Seeking. Neuropsychopharmacology. 2015 Dec;40(13):2981-92.

Molecular Formula	C₂₄H₂₀F₂N₄
Molecular Weight	326.34300
Exact Mass	326.13400
PSA	53.60000
LogP	3.39780

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GSK-1521498

GSK-1521498

Use of GSK-1521498

Names

GSK-1521498 Biological Activity

Chemical & Physical Properties

Synonyms