7-Deaza-2′-deoxyguanosine 5′-triphosphate

Modify Date: 2024-01-14 06:52:42

7-Deaza-2′-deoxyguanosine 5′-triphosphate Structure
7-Deaza-2′-deoxyguanosine 5′-triphosphate structure
Common Name 7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS Number 101515-08-6 Molecular Weight 512.12600
Density 2.48 g/cm3 Boiling Point 907.1ºC at 760 mmHg
Molecular Formula C11H16LiN4O13P3 Melting Point N/A
MSDS USA Flash Point 502.4ºC

 Use of 7-Deaza-2′-deoxyguanosine 5′-triphosphate


7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].

 Names

Name [[5-(2-amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Synonym More Synonyms

  Biological Activity

Description 7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].
Related Catalog
References

[1]. Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.  

 Chemical & Physical Properties

Density 2.48 g/cm3
Boiling Point 907.1ºC at 760 mmHg
Molecular Formula C11H16LiN4O13P3
Molecular Weight 512.12600
Flash Point 502.4ºC
Exact Mass 512.00900
PSA 298.24000
LogP 0.31790
Vapour Pressure 1.76E-35mmHg at 25°C
Index of Refraction 1.854

 Safety Information

RIDADR NONH for all modes of transport

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 Synonyms

7-Deaza-2 inverted exclamation marka-deoxyguanosine 5 inverted exclamation marka-triphosphate lithium salt
7-Deaza-dGTP