7-Deaza-2′-deoxyguanosine 5′-triphosphate

Modify Date: 2024-01-14 06:52:42

7-Deaza-2′-deoxyguanosine 5′-triphosphate Structure
7-Deaza-2′-deoxyguanosine 5′-triphosphate structure
Common Name 7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS Number 101515-08-6 Molecular Weight 512.12600
Density 2.48 g/cm3 Boiling Point 907.1ºC at 760 mmHg
Molecular Formula C11H16LiN4O13P3 Melting Point N/A
MSDS USA Flash Point 502.4ºC

 Use of 7-Deaza-2′-deoxyguanosine 5′-triphosphate


7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].

 Names

Name [[5-(2-amino-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-7-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Synonym More Synonyms

  Biological Activity

Description 7-Deaza-2′-deoxyguanosine 5′-triphosphate (7-Deaza-2'-dGTP), a nucleotide analogue, is a telomerase inhibitor (IC50: 11 μM)[1].
Related Catalog
References

[1]. Fletcher TM, et al. Human telomerase inhibition by 7-deaza-2'-deoxypurine nucleoside triphosphates. Biochemistry. 1996 Dec 10;35(49):15611-7.  

 Chemical & Physical Properties

Density 2.48 g/cm3
Boiling Point 907.1ºC at 760 mmHg
Molecular Formula C11H16LiN4O13P3
Molecular Weight 512.12600
Flash Point 502.4ºC
Exact Mass 512.00900
PSA 298.24000
LogP 0.31790
Vapour Pressure 1.76E-35mmHg at 25°C
Index of Refraction 1.854

 Safety Information

RIDADR NONH for all modes of transport

 Articles53

More Articles
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.

Neurosci. Lett. 590 , 116-20, (2015)

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD). Thus, we examined ...

5-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.

Int. J. Geriatr. Psychiatry 30 , 1017-22, (2015)

Associations between environmental risk factors and depression have been reported to be stronger in people with the S allele of the S/L polymorphism in the serotonin transporter gene-linked promoter r...

Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.

Amyotroph. Lateral Scler. Frontotemporal Degener. 15(7-8) , 569-80, (2014)

Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patient...

 Synonyms

7-Deaza-2 inverted exclamation marka-deoxyguanosine 5 inverted exclamation marka-triphosphate lithium salt
7-Deaza-dGTP
Top Suppliers:I want be here

Get all suppliers and price by the below link:

7-Deaza-2′-deoxyguanosine 5′-triphosphate suppliers

7-Deaza-2′-deoxyguanosine 5′-triphosphate price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3