EZ-482
Modify Date: 2024-02-06 19:11:07
EZ-482 structure
|
Common Name | EZ-482 | ||
|---|---|---|---|---|
| CAS Number | 1016456-76-0 | Molecular Weight | 498.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H19ClN4O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EZ-482EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas[1]. |
| Name | EZ-482 |
|---|
| Description | EZ-482, a novel ligand of apolipoprotein (apoE), binds to sites on apoE in the C-terminal domain with Kds of 5-10 μM for apoE3 and apoE4. EZ-482 binds to apoE4 by a unique N-terminal allosteric effect. EZ482 has the potential for Alzheimer’s diseas[1]. |
|---|---|
| Related Catalog | |
| Target |
Kd: 5-10 μM (apoE3 and apoE4)[1] |
| In Vitro | EZ-482 binds to sites on apoE in the C-terminal domain encompassing residues 229-243 and 258-265[1]. EZ-482 (0.5, 1, 5, 10 μM; 1 hour) blocks heparin binding in a concentration-dependent manner[1]. |
| References |
| Molecular Formula | C23H19ClN4O5S |
|---|---|
| Molecular Weight | 498.94 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: EZ-482
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: EZ-482
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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