EG00229 free base
Modify Date: 2024-01-07 16:02:28
EG00229 free base structure
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Common Name | EG00229 free base | ||
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| CAS Number | 1018927-63-3 | Molecular Weight | 497.572 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H19N7O5S3 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of EG00229 free baseEG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM; also demonstrates to have functional effects on cell-migration and VEGF-R2 phosphorylation. |
| Name | EG00229 |
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| Synonym | More Synonyms |
| Description | EG00229 is a specific inhibitor of neuropilin-1 (NRP1)/VEGF-A interaction, inhibits the binding of biotinylated VEGFA to NRP1 with IC50 of 8 uM; also demonstrates to have functional effects on cell-migration and VEGF-R2 phosphorylation. |
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| References | References 1. Powell J, et al. J Med Chem. 2018 May 10;61(9):4135-4154. 2. Jarvis A, et al. J Med Chem. 2010 Mar 11;53(5):2215-26. View Related Products by Target VEGFR |
| Density | 1.8±0.1 g/cm3 |
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| Molecular Formula | C17H19N7O5S3 |
| Molecular Weight | 497.572 |
| Exact Mass | 497.060974 |
| LogP | 0.63 |
| Index of Refraction | 1.810 |
| RIDADR | NONH for all modes of transport |
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| (S)-2-(3-(benzo[c][1,2,5]thiadiazole-4-sulfonamido)thiophene-2-carboxamido)-5-guanidinopentanoic acid |
| EG00229 |
| N2-({3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl}carbonyl)-L-arginine |
| L-Arginine, N2-[[3-[(2,1,3-benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]- |
| MFCD18251520 |
| N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine |