BAY 60-2770
Modify Date: 2024-01-16 17:42:49
BAY 60-2770 structure
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Common Name | BAY 60-2770 | ||
|---|---|---|---|---|
| CAS Number | 1027642-43-8 | Molecular Weight | 623.645 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H33F4NO5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BAY 60-2770BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM; demonstrates vasodilator activity in the pulmonary and systemic vascular beds that is enhanced by ODQ and NOS inhibition. |
| Name | BAY 60-2770 |
|---|
| Description | BAY 60-2770 is an NO-independent activator of sGC (soluble guanylyl cyclase) with EC50 of 5.4 nM; demonstrates vasodilator activity in the pulmonary and systemic vascular beds that is enhanced by ODQ and NOS inhibition. |
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| Related Catalog | |
| In Vivo | BAY 60-2770 (0.1-0.3 mg/Kg; p.o.) attenuates liver fibrosis in two rat models[1]. BAY 60-2770 (1 mg/kg; p.o.; daily from the 10th to the 12th week) results in amelioration of bladder dysfunction in high-fat obese mice[2]. Animal Model: Obese mice[2] Dosage: 1 mg/kg Administration: p.o.; daily from the 10th to the 12th week Result: Ameliorates detrusor dysfunction in obese mice. |
| References |
| Molecular Formula | C35H33F4NO5 |
|---|---|
| Molecular Weight | 623.645 |