COX-2-IN-18

Modify Date: 2024-01-15 08:24:53

COX-2-IN-18 Structure
COX-2-IN-18 structure
Common Name COX-2-IN-18
CAS Number 1038061-96-9 Molecular Weight 389.49
Density N/A Boiling Point N/A
Molecular Formula C18H19N3O3S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of COX-2-IN-18


COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].

 Names

Name COX-2-IN-18

 COX-2-IN-18 Biological Activity

Description COX-2-IN-18 (Compound 3) is a potent inhibitor of COX-2. COX-2-IN-18 possesses good COX-2 inhibitory activity (IC50 = 0.775 μM) compared to the reference drug, Celecoxib (IC50 = 0.153 μM). COX-2-IN-18 has the potential for the research of cancer diseases[1].
Related Catalog
References

[1]. El-Azab AS, et al. Antitumor activity, multitarget mechanisms, and molecular docking studies of quinazoline derivatives based on a benzenesulfonamide scaffold: Cell cycle analysis. Bioorg Chem. 2020;104:104345.

 Chemical & Physical Properties

Molecular Formula C18H19N3O3S2
Molecular Weight 389.49