RO 5203648

Modify Date: 2024-01-11 13:27:26

RO 5203648 Structure
RO 5203648 structure
Common Name RO 5203648
CAS Number 1043491-54-8 Molecular Weight 231.08
Density 1.6±0.1 g/cm3 Boiling Point 351.5±52.0 °C at 760 mmHg
Molecular Formula C9H8Cl2N2O Melting Point N/A
MSDS N/A Flash Point 166.4±30.7 °C

 Use of RO 5203648


RO5203648 is a potent and highly selective partial agonist of TAAR1 (Trace amine-associated receptor 1) with high affinity. RO5203648 demonstrates a novel paradigm for neuropsychiatric therapeutics[1].

 Names

Name RO-5203648
Synonym More Synonyms

 RO 5203648 Biological Activity

Description RO5203648 is a potent and highly selective partial agonist of TAAR1 (Trace amine-associated receptor 1) with high affinity. RO5203648 demonstrates a novel paradigm for neuropsychiatric therapeutics[1].
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References

[1]. Revel FG, et al. Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. Biol Psychiatry. 2012 Dec 1;72(11):934-42.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 351.5±52.0 °C at 760 mmHg
Molecular Formula C9H8Cl2N2O
Molecular Weight 231.08
Flash Point 166.4±30.7 °C
Exact Mass 230.001373
LogP 2.19
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.663
Storage condition 2-8°C

 Synonyms

(4S)-4-(3,4-Dichlorophenyl)-4,5-dihydro-1,3-oxazol-2-amine
2-Oxazolamine, 4-(3,4-dichlorophenyl)-4,5-dihydro-, (4S)-
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