BIBP3226trifluoroacetate
Modify Date: 2024-01-12 12:27:34
BIBP3226trifluoroacetate structure
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Common Name | BIBP3226trifluoroacetate | ||
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| CAS Number | 1068148-47-9 | Molecular Weight | 587.59 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H32F3N5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BIBP3226trifluoroacetateBIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect[1][2]. |
| Name | BIBP3226 TFA |
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| Description | BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect[1][2]. |
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| Related Catalog | |
| Target |
rNPY Y1 receptor:1.1 nM (Ki) hNPFF2:79 nM (Ki) rNPFF:108 nM (Ki) |
| In Vivo | BIBP3226 (0.5, 5μg; i.c.v.) induces an anxiogenic-like effect at the higher dose[1]. Animal Model: Male Wistar rats 270-350 g[1] Dosage: 0.5, 5μg Administration: I.c.v Result: At the dose of 5μg caused an anxiogenic-like effect while the lower dose was ineffective. |
| References |
| Molecular Formula | C29H32F3N5O5 |
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| Molecular Weight | 587.59 |