Thymoctonan

Modify Date: 2024-01-17 18:28:22

Thymoctonan Structure
Thymoctonan structure
Common Name Thymoctonan
CAS Number 107489-37-2 Molecular Weight 918.04500
Density 1.285g/cm3 Boiling Point 1331.1ºC at 760mmHg
Molecular Formula C43H67N9O13 Melting Point N/A
MSDS N/A Flash Point 758.8ºC

 Use of Thymoctonan


Thymoctonan (THF-γ2) is the immunomodulatory octapeptide, thymic humoral factor γ2. Thymoctonan has the half-life less than 6 min at 37 °C in blood from human, rat and mouse[1].

 Names

Name (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[2-[[2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-3-carboxypropanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid
Synonym More Synonyms

 Thymoctonan Biological Activity

Description Thymoctonan (THF-γ2) is the immunomodulatory octapeptide, thymic humoral factor γ2. Thymoctonan has the half-life less than 6 min at 37 °C in blood from human, rat and mouse[1].
Related Catalog
In Vitro Thymoctonan 形成的主要片段在人和大鼠血液中为 Glu-Asp-Gly-Pro-Lys Phe-Leu (2-8)、Asp-Gly Pro-Lys-Phe-Leu (3-8) 和 Glu-Asp Gly-Pro-Rys (2-6),在小鼠血液中为 2-8 和 2-6[1]。
References

[1]. Martignoni M, et al. Degradation of thymic humoral factor γ2 in human, rat and mouse blood: An experimental and theoretical study. Biochim Biophys Acta Proteins Proteom. 2020 Sep;1868(9):140467.  

 Chemical & Physical Properties

Density 1.285g/cm3
Boiling Point 1331.1ºC at 760mmHg
Molecular Formula C43H67N9O13
Molecular Weight 918.04500
Flash Point 758.8ºC
Exact Mass 917.48600
PSA 358.85000
LogP 2.41680
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.564

 Synonyms

THF-gamma2
Thymoctonan
Leu-Glu-Asp-Gly-Pro-Lys-Phe-Leu
C43H67N9O13
thymic humoral factor gamma2
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