![]() HZ52 structure
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Common Name | HZ52 | ||
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CAS Number | 1077626-51-7 | Molecular Weight | 456.000 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 625.3±55.0 °C at 760 mmHg | |
Molecular Formula | C24H26ClN3O2S | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | 332.0±31.5 °C |
Use of HZ52HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes[1]. |
Name | hz52 |
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Synonym | More Synonyms |
Description | HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes[1]. |
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Related Catalog | |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 625.3±55.0 °C at 760 mmHg |
Molecular Formula | C24H26ClN3O2S |
Molecular Weight | 456.000 |
Flash Point | 332.0±31.5 °C |
Exact Mass | 455.143433 |
PSA | 100.41000 |
LogP | 9.07 |
Vapour Pressure | 0.0±1.9 mmHg at 25°C |
Index of Refraction | 1.641 |
RIDADR | NONH for all modes of transport |
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~% HZ52 CAS#:1077626-51-7 |
Literature: Koeberle, Andreas; Zettl, Heiko; Greiner, Christine; Wurglics, Mario; Schubert-Zsilavecz, Manfred; Werz, Oliver Journal of Medicinal Chemistry, 2008 , vol. 51, # 24 p. 8068 - 8076 |
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Octanoic acid, 2-[[4-([1,1'-biphenyl]-4-ylamino)-6-chloro-2-pyrimidinyl]thio]- |
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