Phloroglucinol

Modify Date: 2024-01-02 19:03:30

Phloroglucinol Structure
Phloroglucinol structure
Common Name Phloroglucinol
CAS Number 108-73-6 Molecular Weight 126.110
Density 1.5±0.1 g/cm3 Boiling Point 331.1±12.0 °C at 760 mmHg
Molecular Formula C6H6O3 Melting Point 215-220 °C
MSDS Chinese USA Flash Point 174.9±14.2 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name phloroglucinol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 331.1±12.0 °C at 760 mmHg
Melting Point 215-220 °C
Molecular Formula C6H6O3
Molecular Weight 126.110
Flash Point 174.9±14.2 °C
Exact Mass 126.031693
PSA 60.69000
LogP 0.06
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.677

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SY1050000
CHEMICAL NAME :
Phloroglucinol
CAS REGISTRY NUMBER :
108-73-6
BEILSTEIN REFERENCE NO. :
1341907
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
QR CQ EQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4050 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
991 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
5 mg/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
3 gm/L
REFERENCE :
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 14,251,1981 *** REVIEWS *** TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 47(2),75,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1900 No. of Facilities: 931 (estimated) No. of Industries: 28 No. of Occupations: 16 No. of Employees: 4964 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1900 No. of Facilities: 82 (estimated) No. of Industries: 5 No. of Occupations: 4 No. of Employees: 2785 (estimated) No. of Female Employees: 1381 (estimated)

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H317-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S7-S16-S24/25
RIDADR UN 1170 3/PG 2
WGK Germany 2
RTECS SY1050000
Hazard Class 6.1
HS Code 2907299090

 Synthetic Route

 Customs

HS Code 2907299090
Summary 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

 Articles80

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Porous graphitic carbon (PGC) is an increasingly popular and attractive phase for HPLC on account of its chemical and thermal stability, and its unique separation mechanism. However, native PGC is str...

 Synonyms

Compound No: 538
1,3,5-TRIHYDROXYBENZENE
Phloroglucinol
dilospans
Benzene, 1,3,5-trihydroxy-
Dolopax
Reference source: Negwer
sym-Trihydroxybenzene
1,3,5-Benzenetriol
Benzene-s-triol
1,3,5-trihydroxy benzene
MFCD00002286
Dilospan S
1,3,5-thb
1,3,5-Trihydroxy
Floroglucin
EINECS 203-611-2
Phloroglucin
1,3,5-trishydroxybenzene
Phloroglucine
Nero
4-06-00-07361 (Beilstein Handbook Reference)
Benzene-1,3,5-triol
Sinterol
Dilexan
2,4,6-trihydroxylbenzene
Triogyl
Flocinon
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