Phloroglucide

Modify Date: 2024-01-09 08:53:10

Phloroglucide Structure
Phloroglucide structure
Common Name Phloroglucide
CAS Number 491-45-2 Molecular Weight 234.20500
Density 1.594g/cm3 Boiling Point 529.5ºC at 760 mmHg
Molecular Formula C12H10O5 Melting Point 216-218 ºC (water )
MSDS N/A Flash Point 268.1ºC

 Use of Phloroglucide


Phloroglucide is a natural product that can be isolated from ferns[1].

 Names

Name Phloroglucide
Synonym More Synonyms

 Phloroglucide Biological Activity

Description Phloroglucide is a natural product that can be isolated from ferns[1].
Related Catalog
References

[1]. Harada, et al. Pharmaceutical Studies on Ferns. III. YAKUGAKU ZASSHI, 72(1), 153–154.

 Chemical & Physical Properties

Density 1.594g/cm3
Boiling Point 529.5ºC at 760 mmHg
Melting Point 216-218 ºC (water )
Molecular Formula C12H10O5
Molecular Weight 234.20500
Flash Point 268.1ºC
Exact Mass 234.05300
PSA 101.15000
LogP 1.88160
Vapour Pressure 7.91E-12mmHg at 25°C
Index of Refraction 1.756
Water Solubility Slightly soluble (3.5 g/L) (25 ºC)

 MSDS

Name: Phloroglucide 95+% Material Safety Data Sheet
Synonym: PHB
CAS: 491-45-2
Section 1 - Chemical Product MSDS Name:Phloroglucide 95+% Material Safety Data Sheet
Synonym:PHB

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
491-45-2 Phloroglucide 95+ unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.Hygroscopic (absorbs moisture from the air).Light sensitive.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid if irritation develops or persists. Flush skin with plenty of soap and water.
Ingestion:
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
Remove from exposure and move to fresh air immediately. Get medical aid if cough or other symptoms appear.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Dark room.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 491-45-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: slightly brown
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 300 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H10O5
Molecular Weight: 234.21

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May discolor on exposure to light.
Conditions to Avoid:
Incompatible materials, light, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 491-45-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Phloroglucide - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 491-45-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 491-45-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 491-45-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Risk Phrases 36/37/38
Safety Phrases 24/25
HS Code 2906299090

 Synthetic Route

~75%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Briggs, Malcolm T.; Duncan, Graham L. S.; Thornber, Craig W. Journal of Chemical Research, Miniprint, 1982 , # 9 p. 2461 - 2487

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Pollak; Gebauer-Fuelnegg Monatshefte fuer Chemie, 1926 , vol. 47, p. 549

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Hlasiwetz Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, 1865 , p. 594 Journal fuer Praktische Chemie (Leipzig), 1866 , vol. <1> 97, p. 156 Full Text Show Details Herzig; Pollak Monatshefte fuer Chemie, 1894 , vol. 15, p. 701,703

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Hlasiwetz Jahresbericht ueber die Fortschritte der Chemie und Verwandter Theile Anderer Wissenschaften, 1865 , p. 594 Journal fuer Praktische Chemie (Leipzig), 1866 , vol. <1> 97, p. 156 Full Text Show Details Herzig; Pollak Monatshefte fuer Chemie, 1894 , vol. 15, p. 701,703

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Cross; Bevan Journal of the Chemical Society, 1911 , vol. 99, p. 1455

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Schiff,H. Justus Liebigs Annalen der Chemie, 1874 , vol. 172, p. 358

~%

Phloroglucide Structure

Phloroglucide

CAS#:491-45-2

Literature: Pollak; Gebauer-Fuelnegg Monatshefte fuer Chemie, 1926 , vol. 47, p. 549

 Customs

HS Code 2906299090
Summary 2906299090 other aromatic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

2-(3,5-dihydroxyphenyl)benzene-1,3,5-triol
Biphenyl-2,3',4,5',6-pentaol
Phloroglucide
Phloroglucide hydrate
MFCD00044547
2,4,6,3',5'-Biphenylpentol
Phloroglucinol Impurity 4