ganoderic acid D structure
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Common Name | ganoderic acid D | ||
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CAS Number | 108340-60-9 | Molecular Weight | 514.650 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 688.3±55.0 °C at 760 mmHg | |
Molecular Formula | C30H42O7 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 384.1±28.0 °C |
Use of ganoderic acid DGanoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells[1]. Ganoderic acid D can inhibit the growth of numerous cancer cell lines and it inhibits HeLa human cervical carcinoma cells with an IC50 of 17.3 mM[2]. |
Name | ganoderic acid D |
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Synonym | More Synonyms |
Description | Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells[1]. Ganoderic acid D can inhibit the growth of numerous cancer cell lines and it inhibits HeLa human cervical carcinoma cells with an IC50 of 17.3 mM[2]. |
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Related Catalog | |
Target |
SIRT3 |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 688.3±55.0 °C at 760 mmHg |
Molecular Formula | C30H42O7 |
Molecular Weight | 514.650 |
Flash Point | 384.1±28.0 °C |
Exact Mass | 514.293030 |
PSA | 125.81000 |
LogP | 2.43 |
Vapour Pressure | 0.0±4.9 mmHg at 25°C |
Index of Refraction | 1.559 |
Ganoderic-acid-D |
Lanost-8-en-26-oic acid, 7-hydroxy-3,11,15,23-tetraoxo-, (7β)- |
GanodericacidD |
(7β)-7-Hydroxy-3,11,15,23-tetraoxolanost-8-en-26-oic acid |