Eupalinolide K

Modify Date: 2024-01-03 01:19:52

Eupalinolide K Structure
Eupalinolide K structure
 Common Name Eupalinolide K
CAS Number 108657-10-9 Molecular Weight 362.417
Density 1.2±0.1 g/cm3 Boiling Point 574.4±50.0 °C at 760 mmHg
Molecular Formula C20H26O6 Melting Point N/A
MSDS N/A Flash Point 201.5±23.6 °C

 Use of Eupalinolide K


Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].

 Names

Name (1E,3β,4E,6α,7β,8β)-3-hydroxy-8-[(4-hydroxytigloyl)oxy]germacra-1(10),4,11(13)-trieno-12,6-lactone
Synonym More Synonyms

 Eupalinolide K Biological Activity

Description Eupalinolide K, a sesquiterpene lactones compound from Eupatorium lindleyanum, is a STAT3 inhibitor. Eupalinolide K is a Michael reaction acceptor (MRA) [1].
Related Catalog
Target

STAT3

References

[1]. Yang B, , et al. Precise discovery of a STAT3 inhibitor from Eupatorium lindleyanum and evaluation of its activity of anti-triple-negative breast cancer. Nat Prod Res. 2019 Feb;33(4):477-485.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 574.4±50.0 °C at 760 mmHg
Molecular Formula C20H26O6
Molecular Weight 362.417
Flash Point 201.5±23.6 °C
Exact Mass 362.172943
PSA 93.06000
LogP 2.29
Vapour Pressure 0.0±3.6 mmHg at 25°C
Index of Refraction 1.557

 Synonyms

2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4S,6Z,9S,10Z,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-
3β-hydroxy-8β-[4'-hydroxytigloyloxy]costunolide
(2E)-4-hydroxy-2-methylbut-2-enoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester
(3aR,4S,6Z,9S,10Z,11aR)-9-Hydroxy-6,10-dimethyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate
eupalinolide K
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Chemsrc provides Eupalinolide K(CAS#:108657-10-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of Eupalinolide K are included as well.>> amp version: Eupalinolide K

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