Eupalinolide B

Modify Date: 2024-01-01 19:41:25

Eupalinolide B Structure
Eupalinolide B structure
Common Name Eupalinolide B
CAS Number 877822-40-7 Molecular Weight 462.490
Density 1.24±0.1 g/cm3 (20 ºC 760 Torr) Boiling Point 618.6±55.0 °C at 760 mmHg
Molecular Formula C24H30O9 Melting Point N/A
MSDS N/A Flash Point 205.4±25.0 °C

 Use of Eupalinolide B


Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90[1].

 Names

Name 2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4R,6Z,9S,10Z,11aR)-9-(acetyloxy)-6-[(acetyloxy)methyl]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)
Synonym More Synonyms

 Eupalinolide B Biological Activity

Description Eupalinolide A, isolated from Eupatorium lindleyanum, induces the expression of HSP70 via the activation of HSF1 by inhibiting the interaction between HSF1 and HSP90[1].
Related Catalog
Target

HSF1

References

[1]. Yamashita Y, et al. Purification and characterization of HSP-inducers from Eupatorium lindleyanum. Biochem Pharmacol. 2012;83(7):909-922.

 Chemical & Physical Properties

Density 1.24±0.1 g/cm3 (20 ºC 760 Torr)
Boiling Point 618.6±55.0 °C at 760 mmHg
Molecular Formula C24H30O9
Molecular Weight 462.490
Flash Point 205.4±25.0 °C
Exact Mass 462.188995
PSA 125.43000
LogP 2.50
Vapour Pressure 0.0±4.1 mmHg at 25°C
Index of Refraction 1.541
Storage condition 2-8°C

 Synonyms

2-Butenoic acid, 4-hydroxy-2-methyl-, (3aR,4R,6E,9S,10Z,11aR)-9-(acetyloxy)-6-[(acetyloxy)methyl]-2,3,3a,4,5,8,9,11a-octahydro-10-methyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester, (2E)-
Eupalinolide B
Eupalinolide A
(3aR,4R,6E,9S,10Z,11aR)-9-Acetoxy-6-(acetoxymethyl)-10-methyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydrocyclodeca[b]furan-4-yl (2E)-4-hydroxy-2-methyl-2-butenoate
Eupalinolide G
EupalinolideB
Eupalinolide-B
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